| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50066916 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157879 (CHEMBL765047) |
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| Ki | 5000±n/a nM |
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| Citation |  Alterman, M; Björsne, M; Mühlman, A; Classon, B; Kvarnström, I; Danielson, H; Markgren, PO; Nillroth, U; Unge, T; Hallberg, A; Samuelsson, B Design and synthesis of new potent C2-symmetric HIV-1 protease inhibitors. Use of L-mannaric acid as a peptidomimetic scaffold. J Med Chem41:3782-92 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50066916 |
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| n/a |
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| Name | BDBM50066916 |
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| Synonyms: | (2R,3R,4R,5R)-2,5-Bis-benzyloxy-3,4-dihydroxy-hexanedioic acid bis-{[(S)-2-(4-hydroxy-phenyl)-1-methylcarbamoyl-ethyl]-amide} | CHEMBL332554 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H46N4O10 |
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| Mol. Mass. | 742.814 |
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| SMILES | CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](OCc1ccccc1)[C@H](O)[C@@H](O)[C@@H](OCc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NC |
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| Structure | 
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