| Reaction Details |
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 | Report a problem with these data |
| Target | L-lactate dehydrogenase B chain |
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| Ligand | BDBM50066973 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_96433 (CHEMBL706380) |
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| Ki | 13000±n/a nM |
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| Citation |  Deck, LM; Royer, RE; Chamblee, BB; Hernandez, VM; Malone, RR; Torres, JE; Hunsaker, LA; Piper, RC; Makler, MT; Vander Jagt, DL Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum. J Med Chem41:3879-87 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| L-lactate dehydrogenase B chain |
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| Name: | L-lactate dehydrogenase B chain |
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| Synonyms: | L-lactate dehydrogenase B | L-lactate dehydrogenase B chain | LDH heart subunit | LDH-B | LDH-H | LDHB | LDHB_HUMAN | Lactate dehydrogenase B (LDHB) | Renal carcinoma antigen NY-REN-46 |
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| Type: | Oxidoreductase; homotetramer |
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| Mol. Mass.: | 36635.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 334 |
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| Sequence: | MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK
GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF
IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG
IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY
EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG
LTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL
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| BDBM50066973 |
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| n/a |
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| Name | BDBM50066973 |
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| Synonyms: | 2,3-Dihydroxy-4-isopropyl-6-methyl-7-(4-trifluoromethyl-benzyl)-naphthalene-1-carboxylic acid | CHEMBL338262 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21F3O4 |
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| Mol. Mass. | 418.4056 |
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| SMILES | CC(C)c1c(O)c(O)c(C(O)=O)c2cc(Cc3ccc(cc3)C(F)(F)F)c(C)cc12 |
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| Structure | 
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