| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Ligand | BDBM23334 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_195890 (CHEMBL804190) |
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| Ki | 7.5±n/a nM |
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| Citation |  Lamb, ML; Jorgensen, WL Investigations of neurotrophic inhibitors of FK506 binding protein via Monte Carlo simulations. J Med Chem41:3928-39 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Name: | Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Synonyms: | 12 kDa FK506-binding protein | 12 kDa FKBP | FK506-binding protein 1A | FK506-binding protein 1A (FKBP12) | FKB1A_HUMAN | FKBP-12 | FKBP-1A | FKBP1 | FKBP12 | FKBP1A | Immunophilin FKBP12 | PPIase | PPIase FKBP1A | Peptidyl-prolyl cis-trans isomerase (FKBP) | Rotamase | RyR1/FKBP12 | mTOR/FKBP12A/FKBP12B |
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| Type: | Isomerase |
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| Mol. Mass.: | 11953.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P62942 |
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| Residue: | 108 |
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| Sequence: | MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW
EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
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| BDBM23334 |
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| n/a |
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| Name | BDBM23334 |
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| Synonyms: | 3-(pyridin-3-yl)propyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | CHEMBL6367 | GPI 1046 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H28N2O4 |
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| Mol. Mass. | 360.4473 |
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| SMILES | CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(=O)OCCCc1cccnc1 |r| |
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| Structure | 
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