| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50067447 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_146361 (CHEMBL753809) |
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| Ki | 15±n/a nM |
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| Citation |  Thomas, JB; Zheng, X; Mascarella, SW; Rothman, RB; Dersch, CM; Partilla, JS; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI N-Substituted 9beta-methyl-5-(3-hydroxyphenyl)morphans are opioid receptor pure antagonists. J Med Chem41:4143-9 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM50067447 |
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| n/a |
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| Name | BDBM50067447 |
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| Synonyms: | 3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol | CHEMBL334898 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29NO |
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| Mol. Mass. | 335.4825 |
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| SMILES | C[C@H]1C2CCCC1(CCN2CCc1ccccc1)c1cccc(O)c1 |
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| Structure | 
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