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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Kappa-type opioid receptor | ||
| Ligand | BDBM60212 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_145986 | ||
| Ki | 3.9±n/a nM | ||
| Citation |  Thomas JB; Zheng X; Mascarella SW; Rothman RB; Dersch CM; Partilla JS; Flippen-Anderson JL; George CF; Cantrell BE; Zimmerman DM; Carroll FI N-Substituted 9beta-methyl-5-(3-hydroxyphenyl)morphans are opioid receptor pure antagonists. J Med Chem 41:4143-9 (1998) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Kappa-type opioid receptor | |||
| Name: | Kappa-type opioid receptor | ||
| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | Opiate Kappa 1 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 42744.99 | ||
| Organism: | Cavia porcellus (domestic guinea pig) | ||
| Description: | P41144 | ||
| Residue: | 380 | ||
| Sequence: |
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| BDBM60212 | |||
| n/a | |||
| Name | BDBM60212 | ||
| Synonyms: | (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride | (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride | MLS000069607 | NALTREXONE HYDROCHLORIDE | SMR000058767 | US9107954, naltrexone | cid_5485201 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H23NO4 | ||
| Mol. Mass. | 341.4009 | ||
| SMILES | Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O | ||
| Structure | 
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