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TargetTryptase gamma
LigandBDBM50067526
Substrate/Competitorn/a
Meas. Tech.ChEMBL_210826 (CHEMBL811855)
IC50 65000±n/a nM
Citation Gabriel, BStubbs, MTBergner, AHauptmann, JBode, WStürzebecher, JMoroder, L Design of benzamidine-type inhibitors of factor Xa. J Med Chem41:4240-50 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Tryptase gamma
Name:Tryptase gamma
Synonyms:PRSS31 | Serine protease 31 | TMT | TPSG1 | TRYG1_HUMAN | Transmembrane tryptase | Tryptase | Tryptase gamma | Tryptase gamma heavy chain | Tryptase gamma light chain
Type:PROTEIN
Mol. Mass.:33817.52
Organism:Homo sapiens (Human)
Description:ChEMBL_210833
Residue:321
Sequence:
MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRM
HVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPSGQP
GTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLR
EVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPGDACQDDSGGPLVCQVNGAWVQAGTV
SWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGLFLPGLFLLLVSC
VLLAKCLLHPSADGTPFPAPD
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50067526
n/a
NameBDBM50067526
Synonyms:2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetylamino]-3-(4-carbamimidoyl-phenyl)-propionic acid | CHEMBL341933
TypeSmall organic molecule
Emp. Form.C19H22N6O5S
Mol. Mass.446.48
SMILESNC(=N)c1ccc(CC(NC(=O)CNS(=O)(=O)c2ccc(cc2)C(N)=N)C(O)=O)cc1
Structure
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