| Reaction Details |
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 | Report a problem with these data |
| Target | Vitamin K-dependent protein C |
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| Ligand | BDBM50067527 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_27848 (CHEMBL642273) |
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| Ki | >1000000±n/a nM |
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| Citation |  Gabriel, B; Stubbs, MT; Bergner, A; Hauptmann, J; Bode, W; Stürzebecher, J; Moroder, L Design of benzamidine-type inhibitors of factor Xa. J Med Chem41:4240-50 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vitamin K-dependent protein C |
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| Name: | Vitamin K-dependent protein C |
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| Synonyms: | Activated protein C cofactor | Anticoagulant protein C | Apolipoprotein H | Autoprothrombin IIA | Blood coagulation factor XIV | Coagulation factor V | Coagulation factor V heavy chain | Coagulation factor V light chain | Endothelial protein C receptor | PROC | PROC_HUMAN | Proaccelerin, labile factor | Vitamin K-dependent protein C precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 52067.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 461 |
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| Sequence: | MWQLTSLLLFVATWGISGTPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECI
EEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSC
DCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVK
FPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGA
VLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDI
ALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVL
NFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLV
SWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAP
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| BDBM50067527 |
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| n/a |
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| Name | BDBM50067527 |
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| Synonyms: | 3-(4-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-benzenesulfonylamino)-acetylamino]-propionic acid ethyl ester | CHEMBL137311 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25N5O5S2 |
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| Mol. Mass. | 491.584 |
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| SMILES | CCOC(=O)C(Cc1ccc(cc1)C(N)=N)NC(=O)CNS(=O)(=O)c1ccc(cc1)C(N)=S |
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| Structure | 
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