| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 1 |
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| Ligand | BDBM50067878 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_92805 (CHEMBL703983) |
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| Kd | 290000±n/a nM |
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| Citation |  Wulff, H; Rauer, H; Düring, T; Hanselmann, C; Ruff, K; Wrisch, A; Grissmer, S; Hänsel, W Alkoxypsoralens, novel nonpeptide blockers of Shaker-type K+ channels: synthesis and photoreactivity. J Med Chem41:4542-9 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 1 |
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| Name: | Potassium voltage-gated channel subfamily A member 1 |
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| Synonyms: | KCNA1 | KCNA1_HUMAN | Potassium (voltage dependent) | Potassium voltage-gated channel subfamily A member 1 | Voltage-gated potassium channel | Voltage-gated potassium channel subfamily A member 1/beta-1 | Voltage-gated potassium channel subunit Kv1.1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 56451.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Potassium (voltage dependent) 0 0::Q09470 |
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| Residue: | 495 |
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| Sequence: | MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
IVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRF
FACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVF
RIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIP
DAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETE
GEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTT
ANQNCVNKSKLLTDV
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| BDBM50067878 |
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| n/a |
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| Name | BDBM50067878 |
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| Synonyms: | 9-Methoxy-furo[3',2':4,5]benzo[1,2-b][1,4]oxazin-3-one | CHEMBL141623 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H7NO4 |
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| Mol. Mass. | 217.1776 |
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| SMILES | COc1c2ccoc2cc2oc(=O)cnc12 |
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| Structure | 
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