Ki Summary

Reaction Details

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Target

M-phase inducer phosphatase 1

Ligand

BDBM50068031

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_40087 (CHEMBL655756)

IC50

2200±n/a nM

Citation

Peng, H; Zalkow, LH; Abraham, RT; Powis, G Novel CDC25A phosphatase inhibitors from pyrolysis of 3-alpha-azido-B-homo-6-oxa-4-cholesten-7-one on silica gel. J Med Chem41:4677-80 (1998) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

M-phase inducer phosphatase 1

Name:

M-phase inducer phosphatase 1

Synonyms:

Type:

Protein

Mol. Mass.:

59090.18

Organism:

Homo sapiens (Human)

Description:

P30304

Residue:

524

Sequence:

MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE
QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK
RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP
ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL
WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK
ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI
SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT
DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY
CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL

BDBM50068031

n/a

Name

BDBM50068031

Synonyms:

CHEMBL142455 | [(1R,3aS,4R,5S,7aR)-5-(5-Cyano-1-methylene-pentyl)-1-((R)-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-yl]-acetic acid | [5-(5-Cyano-1-methylene-pentyl)-1-(1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-yl]-acetic acid | [5-(5-Cyano-1-methylene-pentyl)-1-(1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-yl]-acetic acid(HP-19)

Type

Small organic molecule

Emp. Form.

C27H45NO2

Mol. Mass.

415.6517

SMILES

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@H](CC(O)=O)[C@H](CC[C@]12C)C(=C)CCCCC#N

Structure