| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 1 |
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| Ligand | BDBM50068974 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_99998 |
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| IC50 | 6±n/a nM |
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| Citation |  von Sprecher, A; Gerspacher, M; Beck, A; Kimmel, S; Wiestner, H; Anderson, GP; Niederhauser, U; Subramanian, N; Bray, MA Synthesis and SAR of a novel, potent and structurally simple LTD4 antagonist of the quinoline class. Bioorg Med Chem Lett8:965-70 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteinyl leukotriene receptor 1 |
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| Name: | Cysteinyl leukotriene receptor 1 |
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| Synonyms: | CLTR1_CAVPO | CYSLTR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39007.58 |
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| Organism: | GUINEA PIG |
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| Description: | Leukotriene D4 0 GUINEA PIG::Q2NNR5 |
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| Residue: | 340 |
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| Sequence: | MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSA
FQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAM
SFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPP
QDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIV
VTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFF
SGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
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| BDBM50068974 |
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| n/a |
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| Name | BDBM50068974 |
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| Synonyms: | 2,2-Diethyl-N-[3-(7-fluoro-quinolin-2-ylmethoxy)-phenyl]-succinamic acid | CGP-57698 | CHEMBL178221 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25FN2O4 |
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| Mol. Mass. | 424.4647 |
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| SMILES | CCC(CC)(CC(=O)Nc1cccc(OCc2ccc3ccc(F)cc3n2)c1)C(O)=O |
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| Structure | 
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