| Reaction Details |
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 | Report a problem with these data |
| Target | Lactoylglutathione lyase |
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| Ligand | BDBM50241121 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_71305 (CHEMBL686108) |
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| Ki | 4300±n/a nM |
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| Citation |  Ly, HD; Clugston, SL; Sampson, PB; Honek, JF Syntheses and kinetic evaluation of hydroxamate-based peptide inhibitors of glyoxalase I. Bioorg Med Chem Lett8:705-10 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Lactoylglutathione lyase |
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| Name: | Lactoylglutathione lyase |
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| Synonyms: | Aldoketomutase | GLO1 | Glx I | Glyoxalase 1 (GLO1) | Glyoxalase I | Ketone-aldehyde mutase | LGUL_HUMAN | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase |
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| Type: | Enzyme |
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| Mol. Mass.: | 20772.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q04760 |
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| Residue: | 184 |
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| Sequence: | MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQK
CDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNS
DPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKM
ATLM
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| BDBM50241121 |
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| n/a |
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| Name | BDBM50241121 |
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| Synonyms: | (S)-5-((R)-3-(4-bromobenzylthio)-1-(carboxymethylamino)-1-oxopropan-2-ylamino)-2-amino-5-oxopentanoic acid | CHEMBL218644 | S-p-bromobenzyl glutatione | S-p-bromobenzylglutathione |
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| Type | Small organic molecule |
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| Emp. Form. | C17H22BrN3O6S |
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| Mol. Mass. | 476.342 |
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| SMILES | N[C@@H](CCC(=O)N[C@@H](CSCc1ccc(Br)cc1)C(=O)NCC(O)=O)C(O)=O |r| |
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| Structure | 
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