| Reaction Details |
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 | Report a problem with these data |
| Target | Lactoylglutathione lyase |
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| Ligand | BDBM50069025 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_71304 (CHEMBL686107) |
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| IC50 | 209600±n/a nM |
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| Citation |  Ly, HD; Clugston, SL; Sampson, PB; Honek, JF Syntheses and kinetic evaluation of hydroxamate-based peptide inhibitors of glyoxalase I. Bioorg Med Chem Lett8:705-10 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Lactoylglutathione lyase |
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| Name: | Lactoylglutathione lyase |
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| Synonyms: | Aldoketomutase | GLO1 | Glx I | Glyoxalase 1 (GLO1) | Glyoxalase I | Ketone-aldehyde mutase | LGUL_HUMAN | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase |
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| Type: | Enzyme |
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| Mol. Mass.: | 20772.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q04760 |
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| Residue: | 184 |
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| Sequence: | MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQK
CDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNS
DPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKM
ATLM
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| BDBM50069025 |
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| n/a |
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| Name | BDBM50069025 |
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| Synonyms: | 2-Amino-4-[1-(carboxymethyl-carbamoyl)-3-hydroxycarbamoyl-propylcarbamoyl]-butyric acid anion | CHEMBL164263 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H20N4O8 |
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| Mol. Mass. | 348.3092 |
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| SMILES | [NH3+]C(CCC(=O)NC(CCC(=O)NO)C(=O)NCC(O)=O)C([O-])=O |
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| Structure | 
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