| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50069033 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_80095 |
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| Ki | 0.018000±n/a nM |
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| Citation |  Rodgers, JD; Johnson, BL; Wang, H; Erickson-Viitanen, S; Klabe, RM; Bacheler, L; Cordova, BC; Chang, CH Potent cyclic urea HIV protease inhibitors with 3-aminoindazole P2/P2' groups. Bioorg Med Chem Lett8:715-20 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50069033 |
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| n/a |
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| Name | BDBM50069033 |
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| Synonyms: | (4R,5S,6S,7R)-4,7-Dibenzyl-5,6-dihydroxy-1,3-bis-(3-methylamino-1H-indazol-5-ylmethyl)-[1,3]diazepan-2-one | CHEMBL434098 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H40N8O3 |
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| Mol. Mass. | 644.7653 |
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| SMILES | CNc1[nH]nc2ccc(CN3[C@H](Cc4ccccc4)[C@H](O)[C@@H](O)[C@@H](Cc4ccccc4)N(Cc4ccc5n[nH]c(NC)c5c4)C3=O)cc12 |
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| Structure | 
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