| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
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| Ligand | BDBM50069423 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_144140 |
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| Ki | 21±n/a nM |
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| Citation |  Zimmerman, DM; Cantrell, BE; Smith, EC; Nixon, JA; Bruns, RF; Gitter, B; Hipskind, PA; Ornstein, PL; Zarrinmayeh, H; Britton, TC; Schober, DA; Gehlert, DR Structure-activity relationships of a series of 1-substituted-4-methylbenzimidazole neuropeptide Y-1 receptor antagonists. Bioorg Med Chem Lett8:473-6 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 1 |
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| Name: | Neuropeptide Y receptor type 1 |
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| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44399.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
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| Residue: | 384 |
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| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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| BDBM50069423 |
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| n/a |
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| Name | BDBM50069423 |
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| Synonyms: | 4-(4-{3-[2-(4-Chloro-phenoxymethyl)-4-methyl-benzoimidazol-1-yl]-propyl}-piperidin-1-yl)-1-piperidin-1-yl-butan-1-one | CHEMBL145396 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H43ClN4O2 |
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| Mol. Mass. | 551.162 |
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| SMILES | Cc1cccc2n(CCCC3CCN(CCCC(=O)N4CCCCC4)CC3)c(COc3ccc(Cl)cc3)nc12 |
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| Structure | 
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