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TargetLow affinity immunoglobulin epsilon Fc receptor
LigandBDBM50069587
Substrate/Competitorn/a
Meas. Tech.ChEBML_41676
IC50>1000±n/a nM
Citation Bailey, S; Bolognese, B; Buckle, DR; Faller, A; Jackson, S; Louis-Flamberg, P; McCord, M; Mayer, RJ; Marshall, LA; Smith, DG Hydroxamate-based inhibitors of low affinity IgE receptor (CD23) processing. Bioorg Med Chem Lett8:23-8 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Low affinity immunoglobulin epsilon Fc receptor
Name:Low affinity immunoglobulin epsilon Fc receptor
Synonyms:BLAST-2 | CD23A | CD_antigen=CD23 | CLEC4J | FCE2 | FCER2 | FCER2_HUMAN | Fc-epsilon-RII | IGEBF | Immunoglobulin E-binding factor | Immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form | Low affinity immunoglobulin epsilon Fc receptor soluble form | Lymphocyte IgE receptor
Type:PROTEIN
Mol. Mass.:36461.84
Organism:Homo sapiens (Human)
Description:ChEMBL_88888
Residue:321
Sequence:
MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA
ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL
SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG
TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV
DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM
GPDSRPDPDGRLPTPSAPLHS
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  Blast E-value cutoff:
BDBM50069587
n/a
NameBDBM50069587
Synonyms:(R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*4*-hydroxy-2-naphthalen-2-ylmethyl-succinamide | CHEMBL92762
TypeSmall organic molecule
Emp. Form.C31H31N3O4
Mol. Mass.509.5955
SMILESONC(=O)C[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1
Structure
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