Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetLow affinity immunoglobulin epsilon Fc receptor
LigandBDBM50069613
Substrate/Competitorn/a
Meas. Tech.ChEBML_41669
IC50 130±n/a nM
Citation Bailey, S; Bolognese, B; Buckle, DR; Faller, A; Jackson, S; Louis-Flamberg, P; McCord, M; Mayer, RJ; Marshall, LA; Smith, DG Selective inhibition of low affinity IgE receptor (CD23) processing. Bioorg Med Chem Lett8:29-34 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Low affinity immunoglobulin epsilon Fc receptor
Name:Low affinity immunoglobulin epsilon Fc receptor
Synonyms:BLAST-2 | CD23A | CD_antigen=CD23 | CLEC4J | FCE2 | FCER2 | FCER2_HUMAN | Fc-epsilon-RII | IGEBF | Immunoglobulin E-binding factor | Immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form | Low affinity immunoglobulin epsilon Fc receptor soluble form | Lymphocyte IgE receptor
Type:PROTEIN
Mol. Mass.:36461.84
Organism:Homo sapiens (Human)
Description:ChEMBL_88888
Residue:321
Sequence:
MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA
ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL
SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG
TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV
DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM
GPDSRPDPDGRLPTPSAPLHS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50069613
n/a
NameBDBM50069613
Synonyms:(2R,3S)-N*1*-((S)-1-Carbamoyl-2-phenyl-ethyl)-N*4*-hydroxy-2-isobutyl-3-mercaptomethyl-succinamide | CHEMBL324723
TypeSmall organic molecule
Emp. Form.C18H27N3O4S
Mol. Mass.381.49
SMILESCC(C)C[C@H]([C@H](CS)C(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: