| Reaction Details |
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 | Report a problem with these data |
| Target | Low affinity immunoglobulin epsilon Fc receptor |
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| Ligand | BDBM50069614 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_41669 |
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| IC50 | 380±n/a nM |
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| Citation |  Bailey, S; Bolognese, B; Buckle, DR; Faller, A; Jackson, S; Louis-Flamberg, P; McCord, M; Mayer, RJ; Marshall, LA; Smith, DG Selective inhibition of low affinity IgE receptor (CD23) processing. Bioorg Med Chem Lett8:29-34 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Low affinity immunoglobulin epsilon Fc receptor |
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| Name: | Low affinity immunoglobulin epsilon Fc receptor |
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| Synonyms: | BLAST-2 | CD23A | CD_antigen=CD23 | CLEC4J | FCE2 | FCER2 | FCER2_HUMAN | Fc-epsilon-RII | IGEBF | Immunoglobulin E-binding factor | Immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form | Low affinity immunoglobulin epsilon Fc receptor soluble form | Lymphocyte IgE receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36461.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_88888 |
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| Residue: | 321 |
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| Sequence: | MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA
ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL
SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG
TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV
DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM
GPDSRPDPDGRLPTPSAPLHS
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| BDBM50069614 |
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| n/a |
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| Name | BDBM50069614 |
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| Synonyms: | (2R,3S)-2-(2-Biphenyl-4-yl-2-oxo-ethylsulfanylmethyl)-N*1*-hydroxy-3-isobutyl-N*4*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-succinamide | CHEMBL433197 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H39N3O5S |
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| Mol. Mass. | 589.745 |
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| SMILES | CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSCC(=O)c1ccc(cc1)-c1ccccc1)C(=O)NO |
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| Structure | 
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