| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50069816 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_85846 |
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| Ki | 2.3±n/a nM |
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| Citation |  Shih, NY; Aslanian, R; Lupo, AT; Orlando, S; Piwinski, JJ; Green, MJ; Ganguly, AK; West, R; Tozzi, S; Kreutner, W; Hey, JA Trans-4-methyl-3-imidazoyl pyrrolidine as a potent, highly selective histamine H3 receptor agonist in vivo. Bioorg Med Chem Lett8:243-8 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48753.61 |
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| Organism: | GUINEA PIG |
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| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
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| BDBM50069816 |
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| n/a |
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| Name | BDBM50069816 |
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| Synonyms: | 4-((3R,4R)-4-Methyl-pyrrolidin-3-yl)-1H-imidazole | 4-((3R,4R)-4-methylpyrrolidin-3-yl)-1H-imidazole | CHEMBL313127 | SCH-50971 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H13N3 |
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| Mol. Mass. | 151.2089 |
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| SMILES | C[C@H]1CNC[C@@H]1c1cnc[nH]1 |r| |
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| Structure | 
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