| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H3 receptor |
|---|
| Ligand | BDBM50069825 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_85846 |
|---|
| Ki | 2±n/a nM |
|---|
| Citation |  Shih, NY; Aslanian, R; Lupo, AT; Orlando, S; Piwinski, JJ; Green, MJ; Ganguly, AK; West, R; Tozzi, S; Kreutner, W; Hey, JA Trans-4-methyl-3-imidazoyl pyrrolidine as a potent, highly selective histamine H3 receptor agonist in vivo. Bioorg Med Chem Lett8:243-8 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H3 receptor |
|---|
| Name: | Histamine H3 receptor |
|---|
| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48753.61 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
|
|
|
|---|
| BDBM50069825 |
|---|
| n/a |
|---|
| Name | BDBM50069825 |
|---|
| Synonyms: | 4-Pyrrolidin-3-yl-1H-imidazole | CHEMBL79983 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H11N3 |
|---|
| Mol. Mass. | 137.1823 |
|---|
| SMILES | C1CC(CN1)c1cnc[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
