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TargetBeta-2 adrenergic receptor and beta-3 adrenergic receptor
LigandBDBM50070149
Substrate/Competitorn/a
Meas. Tech.ChEBML_38316
IC50 10±n/a nM
Citation Weber AEMathvink RJPerkins LHutchins JECandelore MRTota LStrader CDWyvratt MJFisher MH Potent, selective benzenesulfonamide agonists of the human beta 3 adrenergic receptor. Bioorg Med Chem Lett 8:1101-6 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50070149
n/a
NameBDBM50070149
Synonyms:4-((3S)-3-{[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino}butyl)phenol | CHEMBL12994
TypeSmall organic molecule
Emp. Form.C19H25NO4
Mol. Mass.331.4061
SMILESC[C@@H](CCc1ccc(O)cc1)NC[C@H](O)COc1ccc(O)cc1
Structure
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