| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50070299 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157555 (CHEMBL763307) |
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| Ki | 4.7±n/a nM |
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| Citation |  Janakiraman, MN; Watenpaugh, KD; Tomich, PK; Chong, KT; Turner, SR; Tommasi, RA; Thaisrivongs, S; Strohbach, JW Non-peptidic HIV protease inhibitors: C2-symmetry-based design of bis-sulfonamide dihydropyrones. Bioorg Med Chem Lett8:1237-42 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50070299 |
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| n/a |
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| Name | BDBM50070299 |
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| Synonyms: | 4N-[3-(1-{2-ethyl-4-hydroxy-2-[3-(1-methyl-1H-4-imidazolylsulfonamido)phenyl]-6-oxo-3,6-dihydro-2H-5-pyranyl}propyl)phenyl]-1-methyl-1H-4-imidazolesulfonamide | CHEMBL20565 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H34N6O7S2 |
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| Mol. Mass. | 654.757 |
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| SMILES | CCC(C1C(=O)CC(CC)(OC1=O)c1cccc(NS(=O)(=O)c2cn(C)cn2)c1)c1cccc(NS(=O)(=O)c2cn(C)cn2)c1 |
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| Structure | 
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