| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prothrombin |
|---|
| Ligand | BDBM50070632 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_208901 |
|---|
| Ki | 300±n/a nM |
|---|
| Citation |  Weber, IR; Neidlein, R; von der Saal, W; Grams, F; Leinert, H; Strein, K; Engh, RA; Kucznierz, R Diarylsulfonamides as selective, non-peptidic thrombin inhibitors. Bioorg Med Chem Lett8:1613-8 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prothrombin |
|---|
| Name: | Prothrombin |
|---|
| Synonyms: | Activation peptide fragment 1 | Activation peptide fragment 2 | Coagulation factor II | F2 | Prothrombin precursor | THRB_HUMAN | Thrombin heavy chain | Thrombin light chain |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 70029.57 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00734 |
|---|
| Residue: | 622 |
|---|
| Sequence: | MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLEREC
VEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHV
NITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQE
CSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASA
QAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETG
DGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYI
DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN
DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP
VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST
RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY
GFYTHVFRLKKWIQKVIDQFGE
|
|
|
|---|
| BDBM50070632 |
|---|
| n/a |
|---|
| Name | BDBM50070632 |
|---|
| Synonyms: | 4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-pyridinium | CHEMBL23813 | N-{3-[2-(Pyridin-4-ylamino)-ethoxy]-phenyl}-benzenesulfonamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H19N3O3S |
|---|
| Mol. Mass. | 369.437 |
|---|
| SMILES | O=S(=O)(Nc1cccc(OCCNc2ccncc2)c1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
