| Reaction Details |
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 | Report a problem with these data |
| Target | Peptide deformylase |
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| Ligand | BDBM50071663 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_154319 |
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| Ki | 125000±n/a nM |
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| Citation |  Hu, YJ; Rajagopalan, PT; Pei, D H-phosphonate derivatives as novel peptide deformylase inhibitors. Bioorg Med Chem Lett8:2479-82 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptide deformylase |
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| Name: | Peptide deformylase |
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| Synonyms: | DEF_ECOLI | PDF | Peptide Deformylase | Polypeptide deformylase | def | fms |
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| Type: | Enzyme |
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| Mol. Mass.: | 19323.16 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | The pdf gene from E. coli K12 was cloned and protein was expressed and purified from E. coli BL21(DE3). |
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| Residue: | 169 |
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| Sequence: | MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIV
IDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFE
LEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA
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| BDBM50071663 |
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| n/a |
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| Name | BDBM50071663 |
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| Synonyms: | CHEMBL309477 | H-PHOSPHONATE DERIVATIVE |
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| Type | Small organic molecule |
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| Emp. Form. | C18H28N3O7P |
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| Mol. Mass. | 429.4046 |
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| SMILES | CCCCC(O[PH+](O)[O-])C(=O)NC(CC(C)C)C(=O)Nc1ccc(cc1)[N+]([O-])=O |
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| Structure | 
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