| Reaction Details |
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 | Report a problem with these data |
| Target | Chymotrypsinogen B |
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| Ligand | BDBM50073137 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_216467 (CHEMBL818537) |
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| IC50 | 3400±n/a nM |
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| Citation |  Iijima, K; Katada, J; Yasuda, E; Uno, I; Hayashi, Y N-[2,2-dimethyl-3-(N-(4-cyanobenzoyl)amino)nonanoyl]-L-phenylalanine ethyl ester as a stable ester-type inhibitor of chymotrypsin-like serine proteases: structural requirements for potent inhibition of alpha-chymotrypsin. J Med Chem42:312-23 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymotrypsinogen B |
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| Name: | Chymotrypsinogen B |
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| Synonyms: | Beta-chymotrypsin | CTRB_BOVIN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25751.02 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_216467 |
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| Residue: | 245 |
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| Sequence: | CGVPAIQPVLSGLARIVNGEDAVPGSWPWQVSLQDSTGFHFCGGSLISEDWVVTAAHCGV
TTSDVVVAGEFDQGLETEDTQVLKIGKVFKNPKFSILTVRNDITLLKLATPAQFSETVSA
VCLPSADEDFPAGMLCATTGWGKTKYNALKTPDKLQQATLPIVSNTDCRKYWGSRVTDVM
ICAGASGVSSCMGDSGGPLVCQKNGAWTLAGIVSWGSSTCSTSTPAVYARVTALMPWVQE
TLAAN
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| BDBM50073137 |
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| n/a |
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| Name | BDBM50073137 |
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| Synonyms: | (S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-pentanoylamino]-3-phenyl-propionic acid ethyl ester | CHEMBL109291 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H31N3O4 |
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| Mol. Mass. | 449.542 |
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| SMILES | CCOC(=O)[C@H](Cc1ccccc1)NC(=O)C(C)(C)C(CC)NC(=O)c1ccc(cc1)C#N |
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| Structure | 
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