Reaction Details |
| Report a problem with these data |
Target | Gag-Pol polyprotein [489-587] |
---|
Ligand | BDBM50073259 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_157700 |
---|
Ki | 0.450000±n/a nM |
---|
Citation | Randad, RS; Lubkowska, L; Eissenstat, MA; Gulnik, SV; Yu, B; Bhat, TN; Clanton, DJ; House, T; Stinson, SF; Erickson, JW Unsymmetric nonpeptidic HIV protease inhibitors containing anthranilamide as a P2' ligand. Bioorg Med Chem Lett8:3537-42 (1999) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Gag-Pol polyprotein [489-587] |
---|
Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
BDBM50073259 |
---|
n/a |
---|
Name | BDBM50073259 |
Synonyms: | CHEMBL333407 | [2-((1S,2R,3S,4S)-1-Benzyl-4-tert-butoxycarbonylamino-2,3-dihydroxy-5-phenyl-pentylcarbamoyl)-phenyl]-carbamic acid pyridin-2-ylmethyl ester |
Type | Small organic molecule |
Emp. Form. | C37H42N4O7 |
Mol. Mass. | 654.752 |
SMILES | CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1NC(=O)OCc1ccccn1 |
Structure |
|