| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 1 |
|---|
| Ligand | BDBM50073278 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_52385 |
|---|
| Ki | 7±n/a nM |
|---|
| Citation |  Chambers, RJ; Antognoli, GW; Cheng, JB; Kuperman, AV; Liston, TC; Marfat, A; Owens, BS; Pillar, JS; Shirley, JT; Watson, JW Development of 2,2-dimethylchromanol cysteinyl LT1 receptor antagonists. Bioorg Med Chem Lett8:3577-82 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cysteinyl leukotriene receptor 1 |
|---|
| Name: | Cysteinyl leukotriene receptor 1 |
|---|
| Synonyms: | CLTR1_CAVPO | CYSLTR1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 39007.58 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | Leukotriene D4 0 GUINEA PIG::Q2NNR5 |
|---|
| Residue: | 340 |
|---|
| Sequence: | MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSA
FQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAM
SFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPP
QDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIV
VTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFF
SGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
|
|
|
|---|
| BDBM50073278 |
|---|
| n/a |
|---|
| Name | BDBM50073278 |
|---|
| Synonyms: | CHEMBL331747 | N-{3-[(3S,4R)-6-(5,6-Difluoro-benzothiazol-2-ylmethoxy)-4-hydroxy-2,2-dimethyl-chroman-3-ylmethyl]-phenyl}-C,C,C-trifluoro-methanesulfonamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H23F5N2O5S2 |
|---|
| Mol. Mass. | 614.604 |
|---|
| SMILES | CC1(C)Oc2ccc(OCc3nc4cc(F)c(F)cc4s3)cc2[C@H](O)[C@@H]1Cc1cccc(NS(=O)(=O)C(F)(F)F)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
