| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
|---|
| Ligand | BDBM9235 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_157552 |
|---|
| Ki | 0.500000±n/a nM |
|---|
| Citation |  Salituro, FG; Baker, CT; Court, JJ; Deininger, DD; Kim, EE; Li, B; Novak, PM; Rao, BG; Pazhanisamy, S; Porter, MD; Schairer, WC; Tung, RD Design and synthesis of novel conformationally restricted HIV protease inhibitors. Bioorg Med Chem Lett8:3637-42 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gag-Pol polyprotein [489-587] |
|---|
| Name: | Gag-Pol polyprotein [489-587] |
|---|
| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
|---|
| Type: | Enzyme Subunit |
|---|
| Mol. Mass.: | 10781.16 |
|---|
| Organism: | Human immunodeficiency virus type 1 |
|---|
| Description: | P04585[489-587] |
|---|
| Residue: | 99 |
|---|
| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
|---|
| BDBM9235 |
|---|
| n/a |
|---|
| Name | BDBM9235 |
|---|
| Synonyms: | (2S)-N-(cyclopentylmethyl)-3-[(3S,5R)-3,5-dibenzyl-2-oxopyrrolidin-1-yl]-2-hydroxy-N-(4-methoxyphenyl)propane-1-sulfonamido | CHEMBL324144 | pyrrolidone 7 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C34H42N2O5S |
|---|
| Mol. Mass. | 590.773 |
|---|
| SMILES | COc1ccc(cc1)S(=O)(=O)N(C[C@@H](O)CN1[C@@H](Cc2ccccc2)C[C@H](Cc2ccccc2)C1=O)CC1CCCC1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
