| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50073369 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_157552 |
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| Ki | 17±n/a nM |
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| Citation |  Salituro, FG; Baker, CT; Court, JJ; Deininger, DD; Kim, EE; Li, B; Novak, PM; Rao, BG; Pazhanisamy, S; Porter, MD; Schairer, WC; Tung, RD Design and synthesis of novel conformationally restricted HIV protease inhibitors. Bioorg Med Chem Lett8:3637-42 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50073369 |
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| n/a |
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| Name | BDBM50073369 |
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| Synonyms: | CHEMBL433187 | N-[(S)-3-((S)-3-Benzyl-5-oxo-1,4-diaza-spiro[5.5]undec-4-yl)-2-hydroxy-propyl]-N-cyclopentylmethyl-4-methoxy-benzenesulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C32H45N3O5S |
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| Mol. Mass. | 583.782 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)N(C[C@@H](O)CN1[C@@H](Cc2ccccc2)CNC2(CCCCC2)C1=O)CC1CCCC1 |
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| Structure | 
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