| Reaction Details |
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 | Report a problem with these data |
| Target | Capsid scaffolding protein |
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| Ligand | BDBM50073419 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_158972 |
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| IC50 | 60±n/a nM |
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| Citation |  Dhanak, D; Keenan, RM; Burton, G; Kaura, A; Darcy, MG; Shah, DH; Ridgers, LH; Breen, A; Lavery, P; Tew, DG; West, A Benzothiopyran-4-one based reversible inhibitors of the human cytomegalovirus (HCMV) protease. Bioorg Med Chem Lett8:3677-82 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Capsid scaffolding protein |
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| Name: | Capsid scaffolding protein |
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| Synonyms: | APNG | Assemblin | Assembly protein | Capsid protein P40 | Human cytomegalovirus protease (HCMV Pr) | Human herpes virus 5 capsid protein P40 | Protease precursor | SCAF_HCMVA | UL80 | pPR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73854.16 |
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| Organism: | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) |
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| Description: | ChEMBL_158958 |
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| Residue: | 708 |
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| Sequence: | MTMDEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQGQGQPSLSVALPLN
INHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKV
VEFLSGSYAGLSLSSRRCDDVEAATSLSGSETTPFKHVALCSVGRRRGTLAVYGRDPEWV
TQRFPDLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLLGNSVDALYIRERLPKLRY
DKQLVGVTERESYVKASVSPEAACDIKAASAERSGDSRSQAATPAAGARVPSSSPSPPVE
PPSPVQPPALPASPSVLPAESPPSLSPSEPAEAASMSHPLSAAVPAATAPPGATVAGASP
AVSSLAWPHDGVYLPKDAFFSLLGASRSAVPVMYPGAVAAPPSASPAPLPLPSYPASYGA
PVVGYDQLAARHFADYVDPHYPGWGRRYEPAPSLHPSYPVPPPPSPAYYRRRDSPGGMDE
PPSGWERYDGGHRGQSQKQHRHGGSGGHNKRRKETAAASSSSSDEDLSFPGEAEHGRARK
RLKSHVNSDGGSGGHAGSNQQQQQRYDELRDAIHELKRDLFAARQSSTLLSAALPSAASS
SPTTTTVCTPTGELTSGGGETPTALLSGGAKVAERAQAGVVNASCRLATASGSEAATAGP
STAGSSSCPASVVLAAAAAQAAAASQSPPKDMVDLNRRIFVAALNKLE
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| BDBM50073419 |
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| n/a |
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| Name | BDBM50073419 |
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| Synonyms: | 2-Biphenyl-4-yl-1,1-dioxo-1H-1lambda*6*-thiochromen-4-one | CHEMBL263745 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H14O3S |
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| Mol. Mass. | 346.399 |
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| SMILES | O=C1C=C(c2ccc(cc2)-c2ccccc2)S(=O)(=O)c2ccccc12 |t:2| |
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| Structure | 
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