| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Capsid scaffolding protein |
|---|
| Ligand | BDBM50073422 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_158972 |
|---|
| IC50 | 60±n/a nM |
|---|
| Citation |  Dhanak, D; Keenan, RM; Burton, G; Kaura, A; Darcy, MG; Shah, DH; Ridgers, LH; Breen, A; Lavery, P; Tew, DG; West, A Benzothiopyran-4-one based reversible inhibitors of the human cytomegalovirus (HCMV) protease. Bioorg Med Chem Lett8:3677-82 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Capsid scaffolding protein |
|---|
| Name: | Capsid scaffolding protein |
|---|
| Synonyms: | APNG | Assemblin | Assembly protein | Capsid protein P40 | Human cytomegalovirus protease (HCMV Pr) | Human herpes virus 5 capsid protein P40 | Protease precursor | SCAF_HCMVA | UL80 | pPR |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 73854.16 |
|---|
| Organism: | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) |
|---|
| Description: | ChEMBL_158958 |
|---|
| Residue: | 708 |
|---|
| Sequence: | MTMDEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQGQGQPSLSVALPLN
INHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKV
VEFLSGSYAGLSLSSRRCDDVEAATSLSGSETTPFKHVALCSVGRRRGTLAVYGRDPEWV
TQRFPDLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLLGNSVDALYIRERLPKLRY
DKQLVGVTERESYVKASVSPEAACDIKAASAERSGDSRSQAATPAAGARVPSSSPSPPVE
PPSPVQPPALPASPSVLPAESPPSLSPSEPAEAASMSHPLSAAVPAATAPPGATVAGASP
AVSSLAWPHDGVYLPKDAFFSLLGASRSAVPVMYPGAVAAPPSASPAPLPLPSYPASYGA
PVVGYDQLAARHFADYVDPHYPGWGRRYEPAPSLHPSYPVPPPPSPAYYRRRDSPGGMDE
PPSGWERYDGGHRGQSQKQHRHGGSGGHNKRRKETAAASSSSSDEDLSFPGEAEHGRARK
RLKSHVNSDGGSGGHAGSNQQQQQRYDELRDAIHELKRDLFAARQSSTLLSAALPSAASS
SPTTTTVCTPTGELTSGGGETPTALLSGGAKVAERAQAGVVNASCRLATASGSEAATAGP
STAGSSSCPASVVLAAAAAQAAAASQSPPKDMVDLNRRIFVAALNKLE
|
|
|
|---|
| BDBM50073422 |
|---|
| n/a |
|---|
| Name | BDBM50073422 |
|---|
| Synonyms: | 2-(4-Nitro-phenyl)-1,1-dioxo-1H-1lambda*6*-thiochromen-4-one | CHEMBL121931 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H9NO5S |
|---|
| Mol. Mass. | 315.301 |
|---|
| SMILES | [O-][N+](=O)c1ccc(cc1)C1=CC(=O)c2ccccc2S1(=O)=O |t:10| |
|---|
| Structure | 
|
|---|
Search and Browse
