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Target5-hydroxytryptamine receptor 1D
LigandBDBM50073682
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1728 (CHEMBL616933)
Ki 2.3±n/a nM
Citation Xu, YC; Schaus, JM; Walker, C; Krushinski, J; Adham, N; Zgombick, JM; Liang, SX; Kohlman, DT; Audia, JE N-Methyl-5-tert-butyltryptamine: A novel, highly potent 5-HT1D receptor agonist. J Med Chem42:526-31 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1D
Name:5-hydroxytryptamine receptor 1D
Synonyms:5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:41920.63
Organism:Homo sapiens (Human)
Description:Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:377
Sequence:
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
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  Blast E-value cutoff:
BDBM50073682
n/a
NameBDBM50073682
Synonyms:CHEMBL1278 | N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide | N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide | N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide | NARATRIPTAN
TypeSmall organic molecule
Emp. Form.C17H25N3O2S
Mol. Mass.335.464
SMILESCNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1
Structure
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