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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Matrix metalloproteinase-9 | ||
| Ligand | BDBM50073885 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_105232 | ||
| IC50 | 14±n/a nM | ||
| Citation |  Fink, CA; Carlson, JE; Boehm, C; McTaggart, P; Qiao, Y; Doughty, J; Ganu, V; Melton, R; Goldberg, R Design and synthesis of thiol containing inhibitors of matrix metalloproteinases. Bioorg Med Chem Lett9:195-200 (1999) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Matrix metalloproteinase-9 | |||
| Name: | Matrix metalloproteinase-9 | ||
| Synonyms: | MMP9_RAT | Matrix metalloproteinase 9 | Matrix metalloproteinase-9 (MMP-9) | Mmp9 | ||
| Type: | n/a | ||
| Mol. Mass.: | 78603.01 | ||
| Organism: | Rattus norvegicus (Rat) | ||
| Description: | P50282 | ||
| Residue: | 708 | ||
| Sequence: |
| ||
| BDBM50073885 | |||
| n/a | |||
| Name | BDBM50073885 | ||
| Synonyms: | 4-Ethoxy-1-mercaptomethyl-cyclohexanecarboxylic acid [(S)-2-(4-hydroxy-phenyl)-1-phenylcarbamoyl-ethyl]-amide | CHEMBL291799 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H32N2O4S | ||
| Mol. Mass. | 456.598 | ||
| SMILES | CCO[C@H]1CC[C@](CS)(CC1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccccc1 |wU:6.11,14.14,3.2,wD:6.6,(-4.06,-11.34,;-4.06,-9.8,;-2.73,-9.05,;-2.73,-7.51,;-4.04,-6.74,;-4.04,-5.2,;-2.73,-4.43,;-4.06,-3.66,;-4.06,-2.12,;-1.38,-5.2,;-1.38,-6.74,;-1.38,-3.66,;-1.38,-2.12,;-.05,-4.43,;1.28,-3.66,;1.28,-2.12,;2.03,-.77,;1.25,.55,;1.99,1.89,;3.53,1.92,;4.28,3.27,;4.33,.6,;3.57,-.75,;2.61,-4.43,;2.61,-5.97,;3.95,-3.66,;5.27,-4.43,;6.62,-3.64,;7.96,-4.41,;7.96,-5.95,;6.62,-6.72,;5.29,-5.97,)| | ||
| Structure | 
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