| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
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| Ligand | BDBM50074007 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_34022 |
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| Ki | 10±n/a nM |
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| Citation |  Nerenberg, JB; Erb, JM; Bergman, JM; O'Malley, S; Chang, RS; Scott, AL; Broten, TP; Bock, MG 4-Oxospiro[benzopyran-2,4'-piperidines] as selective alpha 1a-adrenergic receptor antagonists. Bioorg Med Chem Lett9:291-4 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1A adrenergic receptor |
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| Name: | Alpha-1A adrenergic receptor |
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| Synonyms: | ADA1A_RAT | Adra1a | Adra1c | Alpha-1 adrenoreceptor | Alpha-1A adrenoceptor | Alpha-1A adrenoreceptor | Alpha-1C adrenergic receptor | adrenergic Alpha1A |
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| Type: | Protein |
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| Mol. Mass.: | 51620.15 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P43140 |
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| Residue: | 466 |
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| Sequence: | MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
VPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTL
HPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACT
TARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
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| BDBM50074007 |
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| n/a |
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| Name | BDBM50074007 |
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| Synonyms: | 6-(3,5-dimethyl-4-isoxazolylsulfonamido)-1'-[2-(1-naphthyl)ethyl]-4-oxospiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)] | CHEMBL101610 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H31N3O5S |
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| Mol. Mass. | 545.649 |
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| SMILES | Cc1noc(C)c1S(=O)(=O)Nc1ccc2OC3(CCN(CCc4cccc5ccccc45)CC3)CC(=O)c2c1 |
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| Structure | 
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