| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Pro-cathepsin H |
|---|
| Ligand | BDBM50074052 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_45536 (CHEMBL661056) |
|---|
| Ki | 160000±n/a nM |
|---|
| Citation |  Schirmeister, T New peptidic cysteine protease inhibitors derived from the electrophilic alpha-amino acid aziridine-2,3-dicarboxylic acid. J Med Chem42:560-72 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Pro-cathepsin H |
|---|
| Name: | Pro-cathepsin H |
|---|
| Synonyms: | CATH_HUMAN | CBSP | CPSB | CTSH | Cathepsin H | Cathepsin H heavy chain | Cathepsin H light chain | Cathepsin H mini chain |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 37402.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1459870 |
|---|
| Residue: | 335 |
|---|
| Sequence: | MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS
NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV
DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG
CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV
EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK
NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV
|
|
|
|---|
| BDBM50074052 |
|---|
| n/a |
|---|
| Name | BDBM50074052 |
|---|
| Synonyms: | 1-(2-Benzyloxycarbonylamino-propionyl)-aziridine-2,3-dicarboxylic acid diethyl ester | CHEMBL2371130 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24N2O7 |
|---|
| Mol. Mass. | 392.4031 |
|---|
| SMILES | CCOC(=O)[C@@H]1[C@H](N1C(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)OCC |
|---|
| Structure | 
|
|---|
Search and Browse
