| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50074233 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_30610 (CHEMBL642017) |
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| Ki | 183±n/a nM |
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| Citation |  Li, AH; Moro, S; Forsyth, N; Melman, N; Ji, XD; Jacobson, KA Synthesis, CoMFA analysis, and receptor docking of 3,5-diacyl-2, 4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists. J Med Chem42:706-21 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36643.73 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_479910 |
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| Residue: | 320 |
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| Sequence: | MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALAD
IAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRY
RTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMV
FFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFL
FALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILR
ACRLCQTSDSLDSNLEQTTE
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| BDBM50074233 |
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| n/a |
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| Name | BDBM50074233 |
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| Synonyms: | 4,6-Diethyl-5-ethylsulfanylcarbonyl-2-phenyl-nicotinic acid propyl ester | CHEMBL111086 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27NO3S |
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| Mol. Mass. | 385.52 |
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| SMILES | CCCOC(=O)c1c(CC)c(C(=O)SCC)c(CC)nc1-c1ccccc1 |
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| Structure | 
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