| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-alpha |
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| Ligand | BDBM50074296 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_196913 (CHEMBL807375) |
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| Ki | 21±n/a nM |
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| Citation |  Canan Koch, SS; Dardashti, LJ; Cesario, RM; Croston, GE; Boehm, MF; Heyman, RA; Nadzan, AM Synthesis of retinoid X receptor-specific ligands that are potent inducers of adipogenesis in 3T3-L1 cells. J Med Chem42:742-50 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor RXR-alpha |
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| Name: | Retinoic acid receptor RXR-alpha |
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| Synonyms: | NR2B1 | Nuclear receptor subfamily 2 group B member 1 | Nuclear receptor subfamily 4 group A member 2 | Nuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha | RXRA | RXRA_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoid X receptor alpha | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50820.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1456363 |
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| Residue: | 462 |
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| Sequence: | MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPING
MGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVP
AHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
KRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAEL
AVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVIL
LRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDM
QMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLL
RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
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| BDBM50074296 |
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| n/a |
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| Name | BDBM50074296 |
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| Synonyms: | 4-[[(E)-Isobutoxyimino]-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-methyl]-benzoic acid | CHEMBL351943 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H35NO3 |
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| Mol. Mass. | 421.5717 |
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| SMILES | CC(C)CO\N=C(/c1ccc(cc1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C |
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| Structure | 
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