| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-beta |
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| Ligand | BDBM50074304 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_197080 (CHEMBL806009) |
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| Ki | 6±n/a nM |
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| Citation |  Canan Koch, SS; Dardashti, LJ; Cesario, RM; Croston, GE; Boehm, MF; Heyman, RA; Nadzan, AM Synthesis of retinoid X receptor-specific ligands that are potent inducers of adipogenesis in 3T3-L1 cells. J Med Chem42:742-50 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor RXR-beta |
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| Name: | Retinoic acid receptor RXR-beta |
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| Synonyms: | NR2B2 | Nuclear receptor subfamily 2 group B member 2 | RXRB | RXRB_HUMAN | Retinoic acid receptor RXR-beta | Retinoid X receptor beta | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56932.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_39045 |
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| Residue: | 533 |
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| Sequence: | MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRV
LTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYP
EQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
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| BDBM50074304 |
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| n/a |
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| Name | BDBM50074304 |
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| Synonyms: | 4-{(3-Bromo-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-[(E)-hydroxyimino]-methyl}-benzoic acid | CHEMBL348797 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24BrNO3 |
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| Mol. Mass. | 430.335 |
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| SMILES | CC1(C)CCC(C)(C)c2cc(C(N=O)c3ccc(cc3)C(O)=O)c(Br)cc12 |
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| Structure | 
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