| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase G2 |
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| Ligand | BDBM50074679 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_45646 (CHEMBL873194) |
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| Ki | 5800±n/a nM |
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| Citation |  Khan, TH; Eno-Amooquaye, EA; Searle, F; Browne, PJ; Osborn, HM; Burke, PJ Novel inhibitors of carboxypeptidase G2 (CPG2): potential use in antibody-directed enzyme prodrug therapy. J Med Chem42:951-6 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase G2 |
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| Name: | Carboxypeptidase G2 |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44005.37 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | ChEMBL_302801 |
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| Residue: | 412 |
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| Sequence: | MHARRLPRLLPLALAFLLSPAAFAADTPAAELLRQAEAERPAYLDTLRQLVAVDSGTGQA
EGLGQLSALLAERLQALGAQVRSAPATPSAGDNLVATLDGTGSKRFLLMIHYDTVFAAGS
AAKRPFREDAERAYGPGVADAKGGVAMVLHALALLRQQGFRDYGRITVLFNPDEETGSAG
SKQLIAELARQQDYVFSYEPPDRDAVTVATNGIDGLLLEVKGRSSHAGSAPEQGRNAILE
LSHQLLRLKDLGDPAKGTTLNWTLARGGEKRNIIPAEASAEADMRYSDPAESERVLADAR
KLTGERLVADTEVSLRLDKGRPPLVKNPASQRLAETAQTLYGRIGKRIEPIAMRFGTDAG
YAYVPGSDKPAVLETLGVVGAGLHSEAEYLELSSIAPRLYLTVALIRELSAD
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| BDBM50074679 |
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| n/a |
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| Name | BDBM50074679 |
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| Synonyms: | 2-(4-Amino-phenylsulfanylcarbonylamino)-pentanedioic acid | CHEMBL174759 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H14N2O5S |
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| Mol. Mass. | 298.315 |
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| SMILES | Nc1ccc(SC(=O)NC(CCC(O)=O)C(O)=O)cc1 |
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| Structure | 
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