| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
|---|
| Ligand | BDBM50075805 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_143824 |
|---|
| Ki | 4.5±n/a nM |
|---|
| Citation |  Zarrinmayeh, H; Zimmerman, DM; Cantrell, BE; Schober, DA; Bruns, RF; Gackenheimer, SL; Ornstein, PL; Hipskind, PA; Britton, TC; Gehlert, DR Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists. Bioorg Med Chem Lett9:647-52 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuropeptide Y receptor type 1 |
|---|
| Name: | Neuropeptide Y receptor type 1 |
|---|
| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44399.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
|---|
| Residue: | 384 |
|---|
| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
|
|
|
|---|
| BDBM50075805 |
|---|
| n/a |
|---|
| Name | BDBM50075805 |
|---|
| Synonyms: | 2-Phenoxymethyl-4-(3-piperidin-1-yl-propoxy)-1-(3-piperidin-4-yl-propyl)-1H-benzoimidazole | CHEMBL265752 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H42N4O2 |
|---|
| Mol. Mass. | 490.6801 |
|---|
| SMILES | C(COc1cccc2n(CCCC3CCNCC3)c(COc3ccccc3)nc12)CN1CCCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
