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TargetD(4) dopamine receptor
LigandBDBM50077001
Substrate/Competitorn/a
Meas. Tech.ChEBML_63105
Ki 0.390000±n/a nM
Citation Moore, KWBonner, KJones, EAEmms, FLeeson, PDMarwood, RPatel, SPatel, SRowley, MThomas, SCarling, RW 4-N-linked-heterocyclic piperidine derivatives with high affinity and selectivity for human dopamine D4 receptors. Bioorg Med Chem Lett9:1285-90 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
D(4) dopamine receptor
Name:D(4) dopamine receptor
Synonyms:D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:Enzyme
Mol. Mass.:48373.19
Organism:Homo sapiens (Human)
Description:P21917
Residue:419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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  Blast E-value cutoff:
BDBM50077001
n/a
NameBDBM50077001
Synonyms:1-Benzyl-4-(3-methyl-4-phenyl-pyrazol-1-yl)-piperidine | CHEMBL279247
TypeSmall organic molecule
Emp. Form.C22H25N3
Mol. Mass.331.454
SMILESCc1nn(cc1-c1ccccc1)C1CCN(Cc2ccccc2)CC1
Structure
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