Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50077066 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_145335 (CHEMBL750570) |
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IC50 | 8±n/a nM |
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Citation | Barn, DR; Bom, A; Cottney, J; Caulfield, WL; Morphy, JR Synthesis of novel analogues of the delta opioid ligand SNC-80 using AlCl3-promoted aminolysis. Bioorg Med Chem Lett9:1329-34 (1999) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM50077066 |
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n/a |
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Name | BDBM50077066 |
Synonyms: | 4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide | CHEMBL24035 | CHEMBL544641 |
Type | Small organic molecule |
Emp. Form. | C25H33N3O |
Mol. Mass. | 391.549 |
SMILES | CCN(CC)C(=O)c1ccc(cc1)C(N1CCN(CC=C)CC1)c1ccccc1 |
Structure |
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