| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50077360 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_88774 (CHEMBL878464) |
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| IC50 | 1000±n/a nM |
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| Citation |  Reddy, MV; Rao, MR; Rhodes, D; Hansen, MS; Rubins, K; Bushman, FD; Venkateswarlu, Y; Faulkner, DJ Lamellarin alpha 20-sulfate, an inhibitor of HIV-1 integrase active against HIV-1 virus in cell culture. J Med Chem42:1901-7 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50077360 |
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| n/a |
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| Name | BDBM50077360 |
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| Synonyms: | 3,10-Dihydroxy-13-(3-hydroxy-4-methoxy-phenyl)-2,11-dimethoxy-5-oxa-6b-aza-dibenzo[a,i]fluoren-6-one | CHEMBL301226 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H21NO8 |
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| Mol. Mass. | 499.4682 |
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| SMILES | COc1ccc(cc1O)-c1c2c(n3ccc4cc(O)c(OC)cc4c13)c(=O)oc1cc(O)c(OC)cc21 |
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| Structure | 
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