| Reaction Details |
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 | Report a problem with these data |
| Target | Protein kinase C gamma type |
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| Ligand | BDBM50078562 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_161301 (CHEMBL772109) |
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| Ki | >500±n/a nM |
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| Citation |  Wender, PA; Lippa, B; Park, CM; Irie, K; Nakahara, A; Ohigashi, H Selective binding of bryostatin analogues to the cysteine rich domains of protein kinase C isozymes. Bioorg Med Chem Lett9:1687-90 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein kinase C gamma type |
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| Name: | Protein kinase C gamma type |
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| Synonyms: | KPCG_HUMAN | PKC gamma | PKC-gamma | PKCG | PRKCG | Protein kinase C gamma | Protein kinase C gamma type | Protein kinase C, PKC; classical/novel | Protein kinase C, gamma |
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| Type: | Enzyme |
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| Mol. Mass.: | 78458.05 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The recombinant human PKC enzymes were
produced using a baculovirus expression system in SF9 cells
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| Residue: | 697 |
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| Sequence: | MAGLGPGVGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG
KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL
LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTADEIHVTVGEA
RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRL
SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ
KFEACNYPLELYERVRMGPSSSPIPSPSPSPTDPKRCFFGASPGRLHISDFSFLMVLGKG
SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL
HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD
LKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS
FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGS
GPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL
VLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM
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| BDBM50078562 |
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| n/a |
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| Name | BDBM50078562 |
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| Synonyms: | 11,21-dihydroxy-17-[1-hydroxy-(1R)-ethyl]-10,10-dimethyl-13-[1-methyloxycarbonyl-(E)-methylidene]-19-oxo-(1R,3S,7S,11S,12S,17R,21R,23S)-6,18,27,28,29-pentaoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl octanoate | CHEMBL46252 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H62O13 |
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| Mol. Mass. | 738.9018 |
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| SMILES | CCCCCCCC(=O)O[C@H]1\C(CC2C[C@@H](OC(=O)C[C@H](O)C[C@@H]3CCC[C@H](C[C@@H]4CCO[C@@H](O4)\C=C\C(C)(C)[C@]1(O)O2)O3)[C@@H](C)O)=C\C(=O)OC |t:36| |
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| Structure | 
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