| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Matrix metalloproteinase-14 |
|---|
| Ligand | BDBM50078937 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_106782 (CHEMBL718389) |
|---|
| Ki | 26±n/a nM |
|---|
| Citation |  Vassiliou, S; Mucha, A; Cuniasse, P; Georgiadis, D; Lucet-Levannier, K; Beau, F; Kannan, R; Murphy, G; Knäuper, V; Rio, MC; Basset, P; Yiotakis, A; Dive, V Phosphinic pseudo-tripeptides as potent inhibitors of matrix metalloproteinases: a structure-activity study. J Med Chem42:2610-20 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Matrix metalloproteinase-14 |
|---|
| Name: | Matrix metalloproteinase-14 |
|---|
| Synonyms: | MMP-14 | MMP-X1 | MMP14 | MMP14_HUMAN | MT-MMP 1 | MT1-MMP | MT1MMP | MTMMP1 | Matrix Metalloproteinase-14 (MMP-14) | Matrix metalloproteinase 14 | Matrix metalloproteinase-14 | Matrix metalloproteinase-14 (MMP14) | Membrane-type matrix metalloproteinase 1 | Membrane-type-1 matrix metalloproteinase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 65900.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P50281 |
|---|
| Residue: | 582 |
|---|
| Sequence: | MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQS
LSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQ
HNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIF
FAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHE
LGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTT
SRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQF
WRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALF
WMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKG
NKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAA
AVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
|
|
|
|---|
| BDBM50078937 |
|---|
| n/a |
|---|
| Name | BDBM50078937 |
|---|
| Synonyms: | (1-Benzyloxycarbonylamino-ethyl)-{3-benzylsulfanyl-2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-propyl}-phosphinic acid | CHEMBL90622 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H37N4O6PS |
|---|
| Mol. Mass. | 636.698 |
|---|
| SMILES | CC(NC(=O)OCc1ccccc1)P(O)(=O)CC(CSCc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
