| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
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| Ligand | BDBM50078958 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_143983 (CHEMBL752582) |
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| Ki | >10±n/a nM |
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| Citation |  Murakami, Y; Hara, H; Okada, T; Hashizume, H; Kii, M; Ishihara, Y; Ishikawa, M; Shimamura, M; Mihara, S; Kato, G; Hanasaki, K; Hagishita, S; Fujimoto, M 1,3-Disubstituted benzazepines as novel, potent, selective neuropeptide Y Y1 receptor antagonists. J Med Chem42:2621-32 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 1 |
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| Name: | Neuropeptide Y receptor type 1 |
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| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44399.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
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| Residue: | 384 |
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| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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| BDBM50078958 |
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| n/a |
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| Name | BDBM50078958 |
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| Synonyms: | CHEMBL433216 | {3-[2-Oxo-3-(3-phenyl-ureido)-2,3,4,5-tetrahydro-benzo[b]azepin-1-ylmethyl]-phenyl}-carbamic acid methyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C26H26N4O4 |
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| Mol. Mass. | 458.509 |
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| SMILES | COC(=O)Nc1cccc(CN2c3ccccc3CCC(NC(=O)Nc3ccccc3)C2=O)c1 |
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| Structure | 
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