Reaction Details |
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Target | H2-K region expressed gene 2, rat orthologue |
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Ligand | BDBM50079822 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_103872 |
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IC50 | 88000±n/a nM |
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Citation | Jones, AB; Acton, JJ; Rivetna, MN; Cummings, RT; Cubbon, RM; Nichols, EA; Schwartz, CD; Wicker, LS; Hermes, JD Tetrapeptide derived inhibitors of complexation of a class II MHC: the peptide backbone is not inviolate. Bioorg Med Chem Lett9:2109-14 (1999) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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H2-K region expressed gene 2, rat orthologue |
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Name: | H2-K region expressed gene 2, rat orthologue |
Synonyms: | MHC class II | MHC class II region expressed gene KE2, isoform CRA_a |
Type: | PROTEIN |
Mol. Mass.: | 14499.39 |
Organism: | Rattus norvegicus |
Description: | ChEMBL_10342 |
Residue: | 127 |
Sequence: | MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLL
GPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQN
AKAPGKA
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BDBM50079822 |
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n/a |
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Name | BDBM50079822 |
Synonyms: | CHEMBL303059 | [(S)-1-((S)-1-{(S)-1-[((S)-1-Carbamoyl-3-methyl-butyl)-methyl-carbamoyl]-ethylcarbamoyl}-ethylcarbamoyl)-2-phenyl-ethyl]-carbamic acid ethyl ester |
Type | Small organic molecule |
Emp. Form. | C25H39N5O6 |
Mol. Mass. | 505.6071 |
SMILES | CCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N(C)[C@@H](CC(C)C)C(N)=O |
Structure |
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