| Reaction Details |
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 | Report a problem with these data |
| Target | H2-K region expressed gene 2, rat orthologue |
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| Ligand | BDBM50079824 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_103872 |
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| IC50 | 1±n/a nM |
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| Citation |  Jones, AB; Acton, JJ; Rivetna, MN; Cummings, RT; Cubbon, RM; Nichols, EA; Schwartz, CD; Wicker, LS; Hermes, JD Tetrapeptide derived inhibitors of complexation of a class II MHC: the peptide backbone is not inviolate. Bioorg Med Chem Lett9:2109-14 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| H2-K region expressed gene 2, rat orthologue |
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| Name: | H2-K region expressed gene 2, rat orthologue |
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| Synonyms: | MHC class II | MHC class II region expressed gene KE2, isoform CRA_a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 14499.39 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_10342 |
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| Residue: | 127 |
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| Sequence: | MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLL
GPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQN
AKAPGKA
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| BDBM50079824 |
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| n/a |
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| Name | BDBM50079824 |
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| Synonyms: | ((S)-1-{(S)-1-[(S)-(S)-1-(1-Carbamoyl-3-methyl-butylcarbamoyl)-butylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-carbamic acid ethyl ester | ((S)-1-{(S)-1-[(S)-1-((S)-1-Carbamoyl-3-methyl-butylcarbamoyl)-butylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethyl)-carbamic acid ethyl ester | CHEMBL292340 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H48N8O6 |
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| Mol. Mass. | 604.7414 |
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| SMILES | CCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCC)C(=O)N[C@@H](CC(C)C)C(N)=O |
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| Structure | 
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