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TargetMHC class II
LigandBDBM50079828
Substrate/Competitorn/a
Meas. Tech.ChEBML_103872
IC50 1200±n/a nM
Citation Jones ABActon JJRivetna MNCummings RTCubbon RMNichols EASchwartz CDWicker LSHermes JD Tetrapeptide derived inhibitors of complexation of a class II MHC: the peptide backbone is not inviolate. Bioorg Med Chem Lett 9:2109-14 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
MHC class II
Name:MHC class II
Synonyms:H2-K region expressed gene 2, rat orthologue | MHC class II region expressed gene KE2, isoform CRA_a
Type:PROTEIN
Mol. Mass.:14499.39
Organism:Rattus norvegicus
Description:ChEMBL_103872
Residue:127
Sequence:
MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLL
GPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQN
AKAPGKA
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  Blast E-value cutoff:
BDBM50079828
n/a
NameBDBM50079828
Synonyms:CHEMBL63933 | [(S)-1-(1-{(S)-1-[((S)-(S)-1-Carbamoyl-3-methyl-butylamino)-methyl]-butylcarbamoyl}-4-guanidino-butylcarbamoyl)-2-phenyl-ethyl]-carbamic acid ethyl ester
TypeSmall organic molecule
Emp. Form.C29H50N8O5
Mol. Mass.590.7579
SMILESCCC[C@@H](CN[C@@H](CC(C)C)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCC
Structure
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