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TargetMHC class II
LigandBDBM50079830
Substrate/Competitorn/a
Meas. Tech.ChEBML_103872
IC50 45000±n/a nM
Citation Jones ABActon JJRivetna MNCummings RTCubbon RMNichols EASchwartz CDWicker LSHermes JD Tetrapeptide derived inhibitors of complexation of a class II MHC: the peptide backbone is not inviolate. Bioorg Med Chem Lett 9:2109-14 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
MHC class II
Name:MHC class II
Synonyms:H2-K region expressed gene 2, rat orthologue | MHC class II region expressed gene KE2, isoform CRA_a
Type:PROTEIN
Mol. Mass.:14499.39
Organism:Rattus norvegicus
Description:ChEMBL_103872
Residue:127
Sequence:
MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLL
GPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQN
AKAPGKA
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  Blast E-value cutoff:
BDBM50079830
n/a
NameBDBM50079830
Synonyms:CHEMBL414178 | [(S)-1-((S)-1-{[(S)-1-((S)-1-Carbamoyl-3-methyl-butylcarbamoyl)-butylamino]-methyl}-2-methyl-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid ethyl ester
TypeSmall organic molecule
Emp. Form.C28H47N5O5
Mol. Mass.533.7033
SMILESCCC[C@H](NC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCC)C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O
Structure
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