| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
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| Ligand | BDBM50079939 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_3316 (CHEMBL619016) |
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| Ki | >1000±n/a nM |
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| Citation |  Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL N-Substituted (2,3-dihydro-1,4-benzodioxin-2-yl)methylamine derivatives as D(2) antagonists/5-HT(1A) partial agonists with potential as atypical antipsychotic agents. J Med Chem42:3342-55 (1999) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 4 |
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| Name: | 5-hydroxytryptamine receptor 4 |
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| Synonyms: | 5-hydroxytryptamine receptor 4 protein | Serotonin 4 (5-HT4) receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45024.02 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_1297282 |
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| Residue: | 402 |
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| Sequence: | MDKLDANGSSKEGFGSVEKVVLLTFVSAVILMAVLGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDVWIYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRVAVLLAGCWAIPVLISFLPIMQGWNNIGITDLERTSKPRLGQD
LHVIEKRKFHQNSNSTYCIFMVNKPYAITCSVVAFYIPFLLMVLAYWRIYVTAKEHAHQI
QMLQRAGAPAEGRPPSADQHSTHRMRTETKAAKTLCVIMGCFCLCWAPFFVTNVVDPFAD
YSVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPCVAGQTVPC
STTTVNGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
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| BDBM50079939 |
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| n/a |
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| Name | BDBM50079939 |
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| Synonyms: | (7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2-methoxy-phenyl)-piperidin-4-ylmethyl]-amine | CHEMBL418854 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27ClN2O3 |
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| Mol. Mass. | 402.914 |
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| SMILES | COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 |
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| Structure | 
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